Does irbesartan/hydrochlorothiazide interact with foods or drinks?

There are no known interactions between irbesartan/hydrochlorothiazide and foods or drinks. However, since irbesartan/hydrochlorothiazide affects electrolytes, it is important to discuss your intake of electrolytes, including sodium and potassium, with your healthcare provider.

It is unknown if drinking alcohol will affect irbesartan/hydrochlorothiazide. The risk of dizziness may be increased if you drink alcohol while taking irbesartan/hydrochlorothiazide. It is best to limit the amount of alcohol you drink.

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before taking irbesartan/hydrochlorothiazide.

Aliskiren (Tekturna), which is a medicine for high blood pressure 

A supplement or salt-substitute containing potassium

A diuretic, also called a water pill, which is a medicine used to reduce edema (fluid retention) and blood pressure

A nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen, naproxen, and others, which are contained in many prescription and OTC products for pain, swelling, and fever

Lithium, which is a medicine for certain mental health conditions

An angiotensin-converting enzyme (ACE) inhibitor, which is a medicine for high blood pressure, heart failure, and certain kidney problems

An angiotensin II receptor blocker (ARB), which is a medicine for high blood pressure, heart failure, and other heart conditions

A barbiturate, such as phenobarbital, butalbital, or primidone, which is a medicine that may be used to treat insomnia, migraines, or seizures

An opioid, such as oxycodone, morphine, codeine, or fentanyl, which is a medicine used for certain types of pain

Cholestyramine or colestipol, which are sometimes used to lower cholesterol

A corticosteroid, such as prednisone, methylprednisolone, or dexamethasone, which is a medicine for certain inflammatory conditions

Carbamazepine (Tegretol, Carbatrol, and others), which is a medicine commonly used to treat seizures or nerve pain

Any muscle relaxant

Any medicine for diabetes

Any medicine for high blood pressure 

This may not be a complete list of medicines that can interact with irbesartan/hydrochlorothiazide. Always check with your healthcare provider.